PEG1在人和鼠上均為母系印記基因。 The gene PEG1 was imprinted in human and mouse.
舉例來說，人類胰島素生長因子2（IGF2）的基因通常受到銘印的作用，遺傳自母系的基因不會表現。 The human gene for insulin growth factor 2 (IGF2), for instance, normally is imprinted; the maternal copy is deactivated .
父性表達基因3）是一個印跡基因，只有來源於父方的等位基因才表達。 Part I Expression of PEGS in GliomasPEG3 (Paternally Expressed Gene 5) is an imprinted gene of which only the paternal allele is expressed.
目的：研究印跡基因PEG10在胃癌及癌旁組織中的表達情況，探討其對胃癌細胞生長的影響。 Objective To investigate the expression of a novel imprinted gene, PEG10, in human gastric adenocarcinoma, and the effect of PEG10 on cell growth and proliferation of gastric cancer cells.
這種現象主要在印跡基因和X染色體失活區域看到，這些區域中的啟動子區的DNA甲基化導致了基因表達的抑制。 This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.
例如，受銘印基因當中，遭到消音的對偶基因上頭，絕大多數都具有高度的甲基化。 The silent allele of an imprinted gene is almost always highly methylated , for example.
近年來研究表明，一種新的抑癌印跡基因ARHI（NOEY2）的異常參與了一些腫瘤的發生。 Recently researchers find that a new tumor suppressor imprinted gene ARHI(NOEY2)is involved in the onset and progression of cancer.
結論：轉基因雌雄小鼠印記基因IGF2R均表現印記紊亂。 Conclusions:The imprinted gene IGF2R in male and female transgenic mice were express imprinted disorder.